Response surface analyses of antihypertensive effects of angiotensin receptor blockers and amlodipine or hydrochlorothiazide combination therapy in patients with essential hypertension.

Transl Clin Pharmacol · 2023 · PMC10551747 · PMID 37810629

Europe PMC DOI

hedged sentences

0.0593

closest p · 1.2× alpha

0.0593

boldest claim

The sentences

marginally significantp = 0.0593so close (0.05 < p ≤ 0.1)

However, the marginally significant p -value ( p = 0.0593) of the ARB/AML interaction term could indicate a negative interaction, implying that the effect of the combination drug was less than the sum of the component effects.

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marginal significancep = 0.0593so close (0.05 < p ≤ 0.1)

The ARB/AML combination exhibited a negative (infra-additive) interaction with a marginal significance ( p = 0.0593) in present study.

also in 3,086 other papers

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