Inflammation and coagulation abnormalities via the activation of the HMGB1‑RAGE/NF‑κB and F2/Rho pathways in lung injury induced by acute hypoxia.

Int J Mol Med · 2023 · PMC10555482 · PMID 37350396

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highly significantno p-value reported

Compared with the control group, the levels of F2, RAGE and TNF-α in serum in the hypoxia group were increased, with a highly significant difference; the levels of IL-1β and IL-6 were also significantly increased ( Fig. 3 ).

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