Integrated network analysis and metabolomics reveal the molecular mechanism of Yinchen Sini decoction in CCl<sub>4</sub>-induced acute liver injury.

Front Pharmacol · 2023 · PMC10561237 · PMID 37818184

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a decreasing trendno p-value reported

Compared with the model group, ALT and AST levels were significantly lower in all YCSND treated groups, except for the YCSNDH group, which exhibited a decreasing trend in ALT but not significant ( Figures 4E, F ).

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highly significantno p-value reported

We validated the highly significant PI3K signaling pathway predicted by network analysis through RT-qPCR analysis.

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