Barely Significant
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A multidisciplinary approach with immunotherapies for advanced hepatocellular carcinoma.

J Liver Cancer · 2023 · PMC10565553 · PMID 37743048

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may be significantno p-value reported
This includes the distinctive modulation of terminally differentiated effector CD8 + T cells, which could may be significant in the treatment of immunologically “cold” tumors that exhibit poor immunotherapy responses. 28 In a murine HCC model, the combination therapy of anti-CTLA-4 and antiPD-1 monoclonal antibodies increased the infiltration of CD8 + and CD4 + T cells into tumors as compared to monotherapy, while reducing the infiltration of Tregs.

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