Adverse effects of 21 antidepressants on sleep during acute-phase treatment in major depressive disorder: a systemic review and dose-effect network meta-analysis.

Sleep · 2023 · PMC10566234 · PMID 37422714

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a decreasing trendno p-value reported

When it comes to amitriptyline, desvenlafaxine, duloxetine, escitalopram, paroxetine, toludesvenlafaxine, trazodone, and venlafaxine the risks of somnolence gradually increased from low doses to moderate doses and then showed a decreasing trend through the high doses.

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