Under the constant temperature of 323.15 K for 20 min, the characteristic peaks of 664 cm −1 and 1722 cm −1 shifted, and 664 cm −1 showed a decreasing trend with time, whereas 1722 cm −1 showed an increasing trend.
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Ultrasound-assisted continuous crystallization of metastable polymorphic pharmaceutical in a slug-flow tubular crystallizer.
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