Gibbs Energy and Gene Expression Combined as a New Technique for Selecting Drug Targets for Inhibiting Specific Protein-Protein Interactions.

Furthermore, recent progress in data mining, high throughput data generation relative to gene, protein, and metabolic networks, as well as computer simulations of protein–protein interactions [ 4 , 6 ], offers a new and very attractive opportunity to identify those proteins that would have marginal significance in normal cells but would become signaling hubs in cancer cells.

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