Acquired resistance to KRAS G12C small-molecule inhibitors via genetic/nongenetic mechanisms in lung cancer.

Sci Adv · 2023 · PMC10575592 · PMID 37831779

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highly significantno p-value reported

However, the combination of sotorasib and CFZ showed a highly significant inhibition of tumor growth compared to either drug used alone (red line graph, Fig. 7, B and C ).

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