Barely Significant
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A thermodynamic analysis of CLC transporter dimerization in lipid bilayers.

Proc Natl Acad Sci U S A · 2023 · PMC10576108 · PMID 37788312

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may be significantno p-value reported
However, proteins and their surrounding solvent, e.g., water or lipids, can possess high heat capacities due to extensive networks of nonbonded interactions meaning that there may be significant changes in heat capacity associated with changes in protein conformation or assembly ( Discussion ).

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