Two Cases of Advanced Hepatocellular Carcinoma Who Responded Well to the Combination of Durvalumab Plus Tremelimumab After Disease Progression During Atezolizumab Plus Bevacizumab Therapy Under Bevacizumab Withdrawal.

Subsequently, the AFP level showed a decreasing trend but increased rapidly again, and the lesion in the area where DEB-TACE was performed also increased.

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The intrahepatic lesions were also found to be markedly reduced and decreased, although the AFP levels again showed an increasing trend. 18 F-FDG-PET/CT was therefore performed, which showed new mediastinal lymph node and lung metastases, indicating disease progression (Figure 4 ).

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