Lineage replacement and evolution captured by 3 years of the United Kingdom Coronavirus (COVID-19) Infection Survey.

An increasing trend in Ct values from B.1.617.2/Delta onwards It has previously been observed that when an epidemic is growing Ct values tend to be lower since a higher proportion of samples are taken from early infection when viral loads tend to be higher, and hence Ct values tend to be lower [ 32 – 35 ].

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