Novel Alzheimer's disease genes and epistasis identified using machine learning GWAS platform.

Sci Rep · 2023 · PMC10582044 · PMID 37848535

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

marginally significantno p-value reported

In the ADNI cohort, this pairwise interaction between SH3BP4 and APOE was marginally significant but did not pass Bonferroni correction.

also in 26,082 other papers

marginal significanceno p-value reported

While VariantSpark identified SH3BP4 and SASH1 in both cohorts due to their cumulative additive and epistatic effects on AD, the exact epistatic interactions they are involved in were not replicated, although SH3BP4 - APOE showed marginal significance.

also in 5,069 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.