Antisense oligonucleotide-based targeting of Tau-tubulin kinase 1 prevents hippocampal accumulation of phosphorylated tau in PS19 tauopathy mice.

Acta Neuropathol Commun · 2023 · PMC10585748 · PMID 37853497

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a decreasing trendno p-value reported

The volume of pS422 in the CA1 region also showed a decreasing trend in the ASO- Ttbk1 treated group, although it was not significant (Fig. 2 G).

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