Barely Significant
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Causal relationships between blood lipids and major psychiatric disorders: Univariable and multivariable mendelian randomization analysis.

BMC Med Genomics · 2023 · PMC10585856 · PMID 37853421

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hedged sentence
0.0600
closest p · 1.2× alpha
0.0600
boldest claim

The sentences

borderline significancep = 0.06so close (0.05 < p ≤ 0.1)
In addition, the association reported at borderline significance between genetically predicted HDL-C and MDD in the univariable MR model (OR ivw =0.97, 95% CI = 0.95–1.001, p = 0.06) was enhanced in the MVMR model (OR = 0.98, 95% CI = 0.95–0.998, p = 0.03).In contrast, the connotations between genetically expected TC, LDL-C and MDD, the relations between genetically anticipated TG, LDL-C and AD, and the association among genetically expected LDL-C and AD observed in the univariable MR model were diminished and no longer significant in the MVMR model.

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