Regulation of gene expression downstream of a novel Fgf/Erk pathway during Xenopus development.

PLoS One · 2023 · PMC10586617 · PMID 37856433

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highly significantp<3.9e-63actually significant

Genes involved in the Fgf/Mapk pathway are up-regulated by Fgf4 overexpression and Cic knockdown Using the stated selection criteria, 122 genes are significantly up-regulated by Fgf4 overexpression and 457 by Cic knockdown ( S1 Table ; Fig 3A , 3B , 3D and 3E ), with a highly significant (p<3.9e-63) overlap of 65 genes up-regulated in both conditions ( Fig 3B , S4 Table ).

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