Developmental estrogen exposure in mice disrupts uterine epithelial cell differentiation and causes adenocarcinoma via Wnt/β-catenin and PI3K/AKT signaling.

PLoS Biol · 2023 · PMC10586657 · PMID 37856394

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highly significantno p-value reported

Dual feature plots showed an inverse relationship between Olfm4 and both Trp53 and Pik3r1 ; the differences between expression of these 3 genes in DES cluster 5 relative to all other DES clusters were highly significant ( Fig 7D ).

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