borderline significancep = 0.032
When including the tissue-marker of angiogenesis from IHC (pMVD) together with quantitative parameters from mpMRI (K trans , k ep and blood flow) (Table 4 ), pMVD independently predicted biochemical recurrence, with a borderline significance for clinical recurrence (HR 4.1 and 3.2, p = 0.032 and p = 0.093) together with k ep (HR 7.9 and 13.4, p = 0.001 and p = 0.001).