Genomic Characteristics of Carbapenem-Resistant <i>Klebsiella pneumoniae</i> Isolated from Neonatal Patients in Southwest China During 2017-2021.

26 However, other research reported that the resistance rates of CRKP to levofloxaxin, gentamicin and trimethoprim/sulfamethoxazole showed an increasing trend, suggesting the importance of dynamic monitoring. 27 , 28 In addition, most strains showed high resistance rate to the new cephalosporin/beta-lactamase — ceftazidime-avibactam (95.1%), which was regarded as an effective drug for the treatment of CRKP infections, as compared with previously developed antimicrobials such as colistin, aminoglycosides or tigecycline. 29 , 30 Due to the limited availability of effective drugs, the treatment of CRKP infections in children, particularly in newborns, presents a significant challenge.

also in 63,971 other papers