Is sibship composition a risk factor for childhood asthma? Systematic review and meta-analysis.

World J Pediatr · 2023 · PMC10590346 · PMID 36997765

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a slight trendno p-value reported

A slight trend of weakening association with time could potentially be discerned for birth order, with the pooled effect size on the edge of being significant – albeit with df = 2.13—for studies published before 2000 (RR 0.89, 95% CI 0.79–1) compared to later studies (RR 0.93, 95% CI 0.83–1.03).

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