Desipramine induces eryptosis in human erythrocytes, an effect blunted by nitric oxide donor sodium nitroprusside and N-acetyl-L-cysteine but enhanced by Calcium depletion.

The weakest inhibitory effect on desipramine-induced eryptosis, although highly significant, were obtained with the lowest concentrations of SNP (0.5 μM) and NAC (0.1 mM) ( Figure 6d and Table 1 ).

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