highly significantp = 1.2 × 10 −9
3 c pattern, the separations between data-point distributions for all nearest-neighbor pairs of pre -transition States are highly significant in one or both of the ΔHbO 2 Sat ( p = 1.2 × 10 −9 –9.3 × 10 −4 ) or ΔtotalHb ( p = 5.5 × 10 −5 –4.3 × 10 −4 ) dimensions.