Relationships between body fat distribution and metabolic syndrome traits and outcomes: A mendelian randomization study.

Additionally, there may be significant fat volume variation that is genetically driven but not outside expected ranges for each depot and as such may not demonstrate the same relationships as a true pathologic increase in central adiposity.

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A recent large CT study of abdominal traits in 13,422 patients found strong and highly significant associations between VAT and ASAT with diabetes mellitus, hypertension, chronic kidney disease, renal failure, and renal transplant, as well as a significant increase in triglycerides, glycated hemoglobin, blood urea nitrogen, creatinine, and BMI [ 52 ].

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