A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation.

Nucleic Acids Res · 2023 · PMC10602864 · PMID 37650637

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highly significantP = 8 × 10 −54actually significant

We cross-referenced this list with our RNA-seq data and found that ∼35% of differentially genes in the Bend3 KO relative to WT are bivalent; this is a highly significant enrichment ( P = 8 × 10 −54 , Figure 4C ).

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