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Dynamic characterization and interpretation for protein-RNA interactions across diverse cellular conditions using HDRNet.

Nat Commun · 2023 · PMC10603054 · PMID 37884495

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a decreasing trendno p-value reported
15 , we found a decreasing trend of TDP-43 binding to RNA in most of the transcripts, where alteration in the variant resulted in significant changes of binding events in the high-attention region; for example, in transcript ENST00000547986 from K562 cells shown in Fig. 8 a, a mutation of the poly-U binding peak at position 94,971

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