Individual Immune Response to SARS-CoV-2 Infection-The Role of Seasonal Coronaviruses and Human Leukocyte Antigen.

Comparison of the two groups before the first vaccination was given (time point 2) showed that significantly higher antibody levels were measured in the group with a preceding infection: These differences are highly significant for the full spike, S1, S2 and receptor-binding domains ( p -values < 0.01 in Wilcoxon rank-sum test; Figure 8 a and Figure S7 ).

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