In addition, the 4-HNE levels, which we found to be increased in plasma, although with a decreasing trend in all time-points in ALS patients, have been associated with a greater clinical decline over an 18-month follow-up period [ 40 ].
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Effects of Acetyl-L-Carnitine on Oxidative Stress in Amyotrophic Lateral Sclerosis Patients: Evaluation on Plasma Markers and Members of the Neurovascular Unit.
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