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Analysis of gastrin-17 and its related influencing factors in physical examination results.

Immun Inflamm Dis · 2023 · PMC10604568 · PMID 37904688

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a decreasing trendno p-value reported
4 However, throughout the progression of gastric disease, the diagnostic intensity of serum G17 for AG showed a decreasing trend in the later stage. 5 Intriguingly, the increase or decrease of G17 expression can indicate the occurrence risk of gastric cancer. 6 G17 itself is not a direct inducer of gastric cancer, but it can promote some carcinogenic factors, activate multiple signal transduction pathways, exert antiapoptotic and antiinflammatory effects, and induce gastric acid secretion, thus leading to tumorigenesis. 7 This study aims to analyze G17 and its possible influencing factors in healthy people, so as to fathom out the secretory characteristics and application value of G17 in healthy people. 2.

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