The PKG Inhibitor CN238 Affords Functional Protection of Photoreceptors and Ganglion Cells against Retinal Degeneration.

At P24, however, a highly significant ( p -value < 0.01) rescue of rd10 photoreceptors was observed, with an increase in photoreceptor row counts of ≈55% and ≈46% in CN003- and CN238-treated samples (NT = 3.86 ± 1.01; CN003 = 6.01 ± 0.87; CN238 = 5.64 ± 0.32), respectively ( Figure 2 B).

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