Smoking and Diabetes Attenuate Number of CD34<sup>+</sup> Haematopoietic Stem Cells in Peripheral Blood of Patients with Advanced Peripheral Artery Disease.

Int J Mol Sci · 2023 · PMC10607776 · PMID 37895025

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Autologous cell therapy using CD34 + cells for critical leg ischaemia (ACT34-CLI) [ 4 ] showed a borderline significant decrease in the limb amputation rate after intramuscular application of a high dose of G-CSF-mobilised CD34 + cells, thus indicating the number of transplanted stem cells to be one of the important factors of successful treatment.

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