highly significantp < 0.001
LINC01419 and AK021443 showed significantly increasing linear trend estimates (0.696 [0.663–0.727] and 0.688 [0.654–0.720]) with p < 0.001, while mRNA AF070632 showed a highly significant decreasing trend (−0.553 [(−0.595)–(−0.509)] ( p < 0.001) ( Figure 1 ).