The results showed a remarkable and highly significant increase of cleaved caspase-3 as the main apoptotic marker in the combination group [ADU-S100 (20 μg) + CpG ODN (20 μg)].
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Immunotherapy with STING and TLR9 agonists promotes synergistic therapeutic efficacy with suppressed cancer-associated fibroblasts in colon carcinoma.
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