Thus, tools to aid in the early differential diagnosis of MSA would comprise a highly significant advance. α-syn-containing deposits are the histopathologic hallmark of synucleinopathies, but α-syn accumulation is nonetheless heterogeneous in different diseases in terms of its distribution, conformation and seeding capacity.
← all excerpts
The α-synuclein PET tracer [18F] ACI-12589 distinguishes multiple system atrophy from other neurodegenerative diseases.
1
—
—