Heatwave Definition and Impact on Cardiovascular Health: A Systematic Review.

Excluding three outliers (i.e., all-cause CV mortality in Kuwait [ 70 ], out-of-hospital cardiac arrest events in Israel [ 56 ], and acute aortic dissection morbidity in China [ 75 ]), a slight trend of higher risk with increasing deviation of the heat threshold from the mean annual temperature could be observed, yet not with robust statistical evidence, with the coefficient estimated by ordinary least squares linear regression equal to 0.002 ( R 2 = 0.19).

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It is important to assess if there is an overall trend, transversal to different settings, in the relationship between the selected definition of heat and the related results in terms of impact on CV health.

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