Regulation of the somatotropic axis by MYC-mediated miRNA repression.

Front Cell Dev Biol · 2023 · PMC10615138 · PMID 37908640

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did not achieve significanceno p-value reported

Transfection with let-7i or miR-122 decreased IGF1 protein levels by ∼20% but did not achieve significance, while transfection with both let-7i and miR-122 in combination significantly decreased IGF1 protein levels by ∼40% relative to scrambled control ( Figure 3C ).

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