Several layers comprising various types of cells can be differentiated within the tumor microenvironment; an appreciably significant portion of these cells are myeloid-derived immune cells that become immunosuppressive under tumor signaling (myeloid-derived suppressor cells, MDSC) [ 74 , 75 ].
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Protein Tyrosine Phosphatase CD45 As an Immunity Regulator and a Potential Effector of CAR-T therapy.
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