The circadian clock gene bmal1 is necessary for co-ordinated circatidal rhythms in the marine isopod Eurydice pulchra (Leach).

PLoS Genet · 2023 · PMC10617734 · PMID 37856540

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0.0560

closest p · 1.1× alpha

0.0560

boldest claim

The sentences

failed to reach significancep = 0.056so close (0.05 < p ≤ 0.1)

We noticed three long period outliers in Epbmal1i plus another in WT YFPi and removing them generated a Knockdown effect that marginally failed to reach significance (p = 0.056, but one way ANOVA, p = 0.038, Fig 3H ).

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highly significantno p-value reported

Epcry2 and Epbmal1 mRNA levels in the control and knockdown animals over the circadian cycle revealed no circatidal or circadian cycling [ 12 ] but highly significant reductions to 44% and 43% of control WT YFPi values were observed for the cognate transcripts respectively ( Fig 2A and 2C ).

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