Multiscale genetic architecture of donor-recipient differences reveals intronic LIMS1 mismatches associated with kidney transplant survival.

J Clin Invest · 2023 · PMC10617779 · PMID 37676733

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These SNPs showed DNase hypersensitivity, high RegulomeDB scores (Methods) ( 31 ), transcription-favorable histone modifications, and confirmed highly significant eQTL function in multiple tissues for GCC2 based on the genotype-tissue expression (GTEx) project data ( 20 ) ( Supplemental Tables 14 and 15 ).

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