Interestingly, analysis of overall expression of both isoforms and of genes with highest co-expression with STAT5A and STAT5B in the immune cell database of the Correlation AnalyzeR ( 27 ) revealed a highly significant positive, not negative, correlation between the A and B isoform and their co-expressed genes ( Supplemental Figure 2A ).
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GM-CSF-activated STAT5A regulates macrophage functions and inflammation in atherosclerosis.
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