Application of the National Comprehensive Cancer Network-distress thermometer in pediatric patients during autologous and allogeneic hematopoietic stem cell transplantation and relationship to blood parameters of the stress axis.

As in the pediatric patients, the parents showed an increase of DT scores from the day of admission to the day of HSCT, with a peak on the day of HSCT (median 8.5, range 2–10), followed by a decreasing trend in the DT value over the further course of time to day + 7 (median 6.5, range 1–9, DT day + 7 vs. base: p > 0.99), day + 42 (median 3, range 1–10, DT day + 42 vs. base: p = 0.0015), day + 60 (median 4, range 2–6, DT day + 60 vs. base: p = 0.0363) and on the day of discharge (median 3, range 0–4, DT day of discharge vs. base: p < 0.0001).

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Subsequently, they showed an increasing trend over time (Fig. 2 b).

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