Cyclin-G-associated kinase GAK/dAux regulates autophagy initiation via ULK1/Atg1 in glia.

Proc Natl Acad Sci U S A · 2023 · PMC10629559 · PMID 37428930

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an increasing trendno p-value reported

Interestingly, ULK1, ATG13, and BECLIN1 protein levels significantly increased while ATG14 protein levels exhibited an increasing trend upon GAK siRNA treatment, suggesting a general upregulation in autophagy initiation ( Fig. 2 I and J ).

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