Barely Significant
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The burden of rare variants in DPYS gene is a novel predictor of the risk of developing severe fluoropyrimidine-related toxicity.

Hum Genomics · 2023 · PMC10633914 · PMID 37946254

Europe PMCDOI
1
hedged sentence
0.0550
closest p · 1.1× alpha
0.0550
boldest claim

The sentences

borderline significanceP = 0.055so close (0.05 < p ≤ 0.1)
The number of patients with at least one rare DPYS variant differed between groups (12.2% and 4.2% in the “toxicity” and “no-toxicity” groups, respectively), albeit with borderline significance ( P = 0.055).

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