Bu-Fei Yi-Shen Granules Reduce Acute Exacerbations in Patients with GOLD 3-4 COPD: A Randomized Controlled Trial.

The incidence rate and prevalence of COPD are both high, with an increasing trend and heavy disease burden for COPD all over the world, and chronic respiratory diseases have been the third leading cause of death, mostly due to COPD. 1 In China, the prevalence rate of COPD can reach 8.6%, and is higher than 13% among people over 40 years old. 2 , 3 Although the disease-associated burden decreased in the past 30 years, COPD remains a critical public health problem in China. 4 In recent years, a series of studies have been performed and gratifying results have been obtained for COPD.

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