Limited beneficial effects of systemic steroids when added to standard of care treatment of seasonal allergic rhinitis.

The difference of dCSMS between active treatment and placebo was highly significant but so small that the needed number of participants is believed to be increased multiple times to reflect a significant difference in comparison of QoL.The mean total SNOT-22 score was moderate in both groups according to the grading system proposed by Toma and colleagues and did not differ significantly in neither of the groups 14 .

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