Hypothyroidism increases angiotensinogen gene expression associated with vascular smooth muscle cells cholesterol metabolism dysfunction and aorta remodeling in Psammomys obesus.

The measurement of the great nuclear axis length showed a highly significant increase in the hypothyroid VSMCs nuclear axes compared to their corresponding controls (24.9 ± 0.3 versus 21.3 ± 0.4 μm) (Fig. 3 A).

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