β-TCP from 3D-printed composite scaffolds acts as an effective phosphate source during osteogenic differentiation of human mesenchymal stromal cells.

Front Cell Dev Biol · 2023 · PMC10641282 · PMID 37965582

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

a slight trendno p-value reported

The subtraction of BGP leads to a slight trend of upregulation at day 7 and 28 and maintenance at day 14 compared to the osteogenic group.

also in 1,563 other papers

an overall trendno p-value reported

The absence of exogenous BGP leads to an overall trend of upregulated gene expression levels relevant to matrix production of hBM-MSCs cultured on 3D-printed PLGA/β-TCP discs. 3.4 Absence of exogenous BGP upregulates or maintains gene expression of transcription factors involved in the differentiation of hBM-MSCs cultured on 3D-printed PLGA/β-TCP discs under osteogenic conditions SP7, the osterix encoding gene, is an important transcription factor and driver of MSCs differentiation into osteoblasts and therefore used as an osteogenic marker for hBM-MSC osteogenesis.

also in 2,155 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.