Our group found that three tRNA-derived fragments (tRFs) (tRF-3022b, tRF-3030b, and tRF-5008b) showed an increasing trend in CRC tissues. tRF-3022b may affect CRC tumor growth and M2 macrophage polarization by binding to galectin 1 (LGALS1) and macrophage migration inhibitory factor (MIF) [ 111 ].
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Research progress on the biological basis of Traditional Chinese Medicine syndromes of gastrointestinal cancers.
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