Rosmarinic acid, the active component of Rubi Fructus, induces apoptosis of SGC-7901 and HepG2 cells through mitochondrial pathway and exerts anti-tumor effect.

Naunyn Schmiedebergs Arch Pharmacol · 2023 · PMC10643355 · PMID 37338574

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a decreasing trendno p-value reported

4 E and F, the expression of MMP9 protein in HepG2 and SGC-7901 showed a decreasing trend.

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an increasing trendno p-value reported

We also noted an increasing trend in the proportion of late apoptosis, which suggested that RA affects cell viability by inducing apoptosis.

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