MYB insufficiency disrupts proteostasis in hematopoietic stem cells, leading to age-related neoplasia.

Blood · 2023 · PMC10646772 · PMID 36603185

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21 In addition, the 12-month-old Myb +/− HSC showed highly significant enrichment of genes encoding proteins linked with rRNA processing and ribosome biogenesis ( Figure 4 B-C).

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