Evaluation of α-synuclein in CNS-originating extracellular vesicles for Parkinsonian disorders: A systematic review and meta-analysis.

CNS Neurosci Ther · 2023 · PMC10651986 · PMID 37416941

Europe PMC DOI

hedged sentence

0.0620

closest p · 1.2× alpha

0.0620

boldest claim

The sentences

almost reached significancep = 0.062so close (0.05 < p ≤ 0.1)

Adding α‐syn in oEVs 17 , 24 , 25 to the meta‐analysis did not alter the results, although the p‐value almost reached significance ( k = 26, SMD = 0.18; 95% CI −0.01, 0.38; p = 0.062; Figure S1 ).

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