The transcription factor EBF1 non-cell-autonomously regulates cardiac growth and differentiation.

Development · 2023 · PMC10652039 · PMID 37787076

Europe PMC DOI

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Based on the presence of EBF1-binding sites in 13,924 genes, or in 28.58% of the known mouse genome, the enrichment of EBF1 gene targets among the DEGs in LDN-treated samples was highly significant (χ 2 –2939.58, P <0.0001), suggesting an important role for EBF1 in BMP signal transduction.

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